Adult-onset growth hormone deficiency is where the pituitary gland fails to produce enough growth hormone. It can be successfully treated with growth hormone therapy.

Amenorrhoea is the term used to describe a lack of 'periods' (menstrual cycles) in women. The management of amenorrhoea depends on the underlying cause.

Chronic fatigue syndrome (ME/CFS) is a complex condition that causes long-term, fluctuating, and energy-draining fatigue, which does not improve with rest or sleep.

Congenital adrenal hyperplasia is an inherited disorder that results in low levels of cortisol and high levels of male hormones, causing development of male characteristics in females, and early puberty in both boys and girls.

Craniopharyngiomas are rare, slow-growing benign brain tumours which most commonly occur above the pituitary gland, but occasionally are found within the bony cup containing the pituitary gland.

Cushing's disease is the condition resulting from a pituitary tumour secreting excess amounts of adrenocorticotropic hormone (ACTH), which then stimulates the adrenal glands to release excess amounts of the hormone cortisol.

Empty sella syndrome is the term used to describe the appearance of a small, shrunken or absent pituitary gland on pituitary imaging. Most patients have no symptoms, and generally no treatment is required. If hormone deficiencies are present, hormone replacement therapy should be considered.

Endometriosis is a condition in women where the lining of the womb grows outside of the womb causing scar tissue and painful monthly periods.

Gastrinomas are tumours which produce an excessive amount of the hormone called gastrin. These tumours originate from pancreas, stomach and the small intestine.

Gender identity disorder is where a person is dissatisfied with their biological sex, because they feel that it is different from the gender they feel they should be. This often leads to a desire to change their appearance with hormones or surgery and live in their preferred gender.

A glucagonoma is a very rare tumour of the pancreas in which there is an increase in release of the hormone glucagon, causing a characteristic skin rash and raised blood sugar levels.

Graves' disease is an autoimmune thyroid disease. The body produces antibodies against the thyroid gland which can cause it to become overactive, resulting in increased thyroid hormone production and hyperthyroidism.

Hashimoto's disease is an autoimmune disease that causes inflammation of the thyroid gland and results in a reduction in thyroid hormone levels.

Hypercalcaemia is the presence of abnormally high calcium levels in the blood.

Hyperthyroidism is a common condition where the thyroid gland becomes overactive and produces too much thyroid hormone.

Hypocalcaemia refers to low calcium levels in the blood. It is most commonly caused by either vitamin D deficiency or diseases of the parathyroid glands causing low parathyroid hormone (PTH) secretion.

Hyponatraemia means abnormally low levels of sodium (salt) in the bloodstream or a deficiency of sodium in the body.

Hypoparathyroidism is a rare condition characterised by inadequate parathyroid hormone (PTH) secretion from the parathyroid glands, resulting in low calcium levels in the bloodstream.

Hypophosphataemia is the term used to describe low levels of phosphate in the blood. It is most commonly caused by hyperparathyroidism and vitamin D deficiency.

Hypopituitarism is the failure of production of one or more hormones from the pituitary gland.

An insulinoma is a type of tumour that occurs in the pancreas. The tumour secretes too much insulin, which causes blood glucose (sugar) to drop to low levels.

Male hypogonadism is the result of deficiency of the male sex hormone testosterone. It can lead to loss of sex drive and function, delayed puberty, osteoporosis, and there can also be associated failure of the testes to produce sperm.

Multiple endocrine neoplasia type 1 is a rare inherited disease, which can result in tumours in the pituitary and parathyroid glands, and pancreas.

Multiple endocrine neoplasia type 2A (MEN2A) is a rare inherited disease causing the development of tumours in the thyroid, adrenal and parathyroid glands.

Multiple endocrine neoplasia type 2B (MEN2B) is a rare inherited disease causing the development of tumours in the thyroid, adrenal and parathyroid glands, and mucosal tumours.

Nelson's syndrome is the name given to the enlargement of a pituitary gland tumour associated with excess secretion of adrenocorticotropic hormone following the surgical removal of both adrenal glands, usually to treat Cushing's disease.

Non-functioning pancreatic neuroendocrine tumours (NETs) are tumours that originate in specialised cells of the pancreas.

Non-functioning pituitary tumours are the most common benign growths in the pituitary gland. These tumours are usually identified because of impaired vision or hormone deficiencies.

Pituitary apoplexy is a medical emergency. It is caused by either a bleed into and/or death of an area of tissue in the pituitary gland. It is usually associated with the presence of a pituitary tumour.

Pre-eclampsia is a condition that arises during pregnancy in which the expectant mother experiences very high blood pressure and protein in her urine; it can lead to a range of complications.

Menopause usually happens in women over the age of 45 years, but if the ovaries stop working prematurely (i.e. before the age of 40 years), this is called ‘Premature Ovarian Insufficiency’ (POI).

Primary hyperaldosteronism refers to a condition in which one or both adrenal glands generate too much of a hormone called aldosterone. This causes sodium (salt) retention, leading to high blood pressure.

Primary hyperparathyroidism is the release of too much parathyroid hormone from the parathyroid glands causing high levels of calcium in the bloodstream.

A prolactinoma is a benign tumour of the pituitary gland that produces excess amounts of the hormone prolactin. It responds well to medication and surgery is avoidable in the majority of cases.

Resistance to thyroid hormone is a rare genetic condition where some body tissues do not respond normally to thyroid hormones produced by the thyroid gland. It may be associated with no symptoms or with features of both an overactive and underactive thyroid.

Secondary hyperparathyroidism is the release of increased amounts of parathyroid hormone (hyperparathyroidism), which is an appropriate response to low calcium or vitamin D levels in order to try to bring calcium levels back up to normal.

Sheehan's syndrome is a rare condition affecting the pituitary gland that occurs as a result of heavy bleeding during or after childbirth.

Somatostatinomas are rare neuroendocrine tumours that arise from tumour cells originated from specialised hormone-producing cells in the endocrine pancreas and duodenum (first part of small intestine).

Tertiary hyperparathyroidism means excess production of parathyroid hormone that has escaped all normal body feedback controls and so persists even in cases where the initial cause (low blood calcium) has been corrected.

Lifestyle factors such as exercise, dietary factors, smoking cessation and reducing alcohol intake can improve menopause-related symptoms as well as improve heart and bone health.

TSH-secreting pituitary adenomas are slow-growing benign pituitary tumours that produce thyroid stimulating hormone (TSH) and are a very rare cause of hyperthyroidism (overactive thyroid).

Lipodystrophy is a condition in which the amount and/or distribution of adipose tissue (fat tissue) in the body is abnormal. Different types of lipodystrophy cause loss or re-distribution of fat tissue in different patterns.

The increase in prevalence of individuals who are obese or develop metabolic complications like cardiovascular disease, diabetes and non-alcoholic fatty liver disease (NAFLD) is increasing. The development of these diseases is a result of a several of symptoms which are collectively known as metabolic syndrome.